Nanoarchitecture opens new possibilities in building sustainability, it prompts environmental and zero carbon design and delivers new materials which can meet natural execution criteria and impacts of climatic change. The vast majority of present building and engineering concepts are to substitute numerous petrochemically derivatives with bio-based materials from sustainable assets. Scientists endure to achieve progress and defeat the cost of processing plant material into value-added products. The paper brought up the issue of: In the era of developments and blasting of new ideas, for example, sustainability and Nano materials-; Are buildings' maintenance materials and applications anticipated that would react to current advancements? The paper acquainted a connected idea with bio-based and Nano models for the maintenance of building floors. The point was to approve the added value to sustainability that a bio Nano maintenance material can offer better than a traditional chemically produced one. A comparative analysis was carried out for the Nano green mastic remover, and Bean-e-doo mastic remover. The analysis covered the relative performance of both materials in respect to environmental and economic criteria. The comparison was carried out in an online platform using the BEES software. Results demonstrated that the Nano-Green material has less ecological effects, as well as less introductory and future financial expenses too contrasted with the Bean-e-doo mastic remover material. Consequently, the linkage between Bio based and Nano materials on one hand, and sustainable maintenance on the other hand is unmistakably distinguished.